I usually run 75-80% of the wire of what I'd run in flat position. Practice. Lock a piece of tube in the vice thats long enough to weld a piece of plate to the top of from a standing position reaching up, then use some scrap strips and weld "T-fillets" upside down until you like the results from your machine.
It so much easier to practice that way, than "out of position" under a car, arm around the exhaust, and trying to dial it in.
Also throw in a set of earplugs. It will keep hot slag from dropping and getting super highway'd through your eardrums. I now a guy here in Houston that has brain damage from overhead welding and catching slag through the eardrums and into his brain. He's also deaf in that ear now.
Before Bonneville this year I had to do some random overhead, and I was way out of practice. One thing I lacked was all of the "weights" for the car, 4" tubing filled with lead shotgun shot BB's. I had to weld a cap an end, then fill full of shot, then weld the other end. I did all of my cap welding in overhead for practice. A couple of my dads buddies came over and saw and were like WTF. I said I was just eeping up on practice and dialing my welder in for these other pieces. Then they saw my welds they couldnt believe I did it overhead they were so good. Practice!!!